This pilot study was conducted in the framework of SmokeFreeBrain project and it aimed at assessing the subjective emotional impact of skin temperature training and neurofeedback training on smokers by means of the AffectLecture application. The current paper constitutes a proof-of-concept, exploring the case of a single participant. The intervention consists of 5 sessions of biofeedback followed by 20 sessions of neurofeedback. Both pre- and post- biofeedback and neurofeedback training subjective scores of the participant’s mood were collected through the application. Based on our results, biofeedback training seems to promote alterations in mood, which are then maintained in the baseline mood scoring before neurofeedback training. Additionally, mood seems to be preserved after neurofeedback training. However, significant correlations between scoring and training performance have not been indicated.